PhD defence M.S.I.C. (Melissa) Kurniawan

Brief summary:

This thesis examines the long-term outcomes in patients with sagittal craniosynostosis, addressing both functional and aesthetic aspects. The research focuses on improving the use of 3D photogrammetry, comparing surgical techniques, assessing head circumference as a screening method for intracranial hypertension (ICH), and evaluating cognitive profiles and long-term quality of life.

A key theme is the growing use of 3D photogrammetry in craniofacial care. While this technology offers valuable insights into skull and facial shape and growth, the lack of a standardized protocol makes comparing results between studies challenging. A comparative study shows that automated and manual measurements of skull dimensions are highly reliable, benefiting clinical practice.

The comparison of three surgical techniques—frontobiparietal remodeling (FBR), extended strip craniotomy (ESC), and spring-assisted correction (SAC)—reveals that skull shape improves over time, but certain abnormalities, such as a flattened vertex, persist. Head circumference also emerges as an important predictor of papilledema, a potential symptom of ICH, with smaller head sizes being associated with a higher risk.

The study on cognitive outcomes shows that some patients have slightly lower IQs, though still within the normal range. Regarding aesthetic satisfaction, many patients are content with their head shape, though one-third would opt for changes. Finally, the research indicates that while patients with sagittal craniosynostosis experience a slightly lower quality of life, particularly due to headaches, their quality of life remains reasonably comparable to children in the general population who also suffer from frequent headaches.