On Wednesday 27 November 2024, H. Tejeda Mora will defend the doctoral thesis titled: ‘On the Role of Non-Parenchymal Cells in Kidney Transplantation‘.
- Promotor
- Promotor
- Co-promotor
- Co-promotor
- Date
- Wednesday 27 Nov 2024, 13:00 - 14:30
- Type
- PhD defence
- Space
- Professor Andries Querido room
- Building
- Education Center
- Location
- Erasmus MC
Brief summary:
Kidney transplantation is a medical procedure where a healthy kidney from a donor is placed into a person whose kidneys no longer function properly. This is often a life-saving operation for individuals with end-stage kidney disease. The new, functioning kidney takes over the role of clearing waste from the blood, which the patient’s own kidneys can no longer do effectively. As with many medical procedures, kidney transplantation has major challenges, one of the most significant being rejection, which can lead to the failure of the newly transplanted kidney. To help prevent rejection of the graft, various cellular mechanisms are currently being studied, including the cellular responses to injury, the cellular contributions to the organ’s repair, and the cellular roles in immunomodulation. Understanding how cells interact and its dynamics is crucial for gaining new insights into the transplantation field. This thesis aims to extend the understanding of how endothelial cells (EC), tissue-resident memory (TRM) T cells, and membrane particles (MP) derived from mesenchymal stromal cells (MSC) affect the outcome of kidney transplantation and how these cells can be used to aid in rejection prevention
- More information
The public defence will begin exactly at 13.00 hrs. The doors will be closed once the public defence starts, latecomers can access the hall via the fourth floor. Due to the solemn nature of the ceremony, children under the age of 6 are not allowed during the first part of the ceremony.
