- Promotor
- Co-promotor
- Date
- Thursday 26 Sep 2024, 10:30 - 12:00
- Type
- PhD defence
- Space
- Senate Hall
- Building
- Erasmus Building
- Location
- Campus Woudestein
On Thursday 26 September 2024, E.P. Martínez López will defend the doctoral thesis titled: ‘The Association of Antimicrobial Resistance and Antimicrobial Use in Humans and Animals‘.
Brief summary:
Overuse and misuse of antibiotics in both human and veterinary medicine are key drivers for AMR. Previous observational studies analyzed the association of AMU and AMR as linear, which does not fully explain dynamic AMR selection. Longitudinal studies using time series analysis, could capture the underlying dynamic association between AMU and AMR, and provide insight into how changes in AMU lead to future changes in AMR. Such insights would allow us to build and to implement strategies to reduce the impact of AMR in humans and animals.
This thesis focused on two main objectives. In Chapter 2.1 we explored how non-clinical factors can influence antibiotic prescription patterns, and lead to inappropriate AMU. In Chapters 2.2 to 2.5 we explored the complex association of AMU and AMR by analyzing the trends and seasonality of AMU and how this could lead to future changes in AMR in the Netherlands.
Based on our results, future studies regarding the association of AMU and AMR should consider the dynamics between these two variables, including seasonal variations in both AMU and AMR. It is important to point out that most of the studies in this thesis used surveillance data that has been routinely collected for monitoring purposes, remarking the importance of using real-world evidence in contributing to knowledge and for implementing and monitoring strategies to reduce the impact of AMR
- More information
The public defence will begin exactly at 10.30 hrs. The doors will be closed once the public defence starts, latecomers may be able to watch on the screen outside. There is no possibility of entrance during the first part of the ceremony. Due to the solemn nature of the ceremony, children under the age of 6 are not allowed during the first part of the ceremony.