On Tuesday 19 March 2024, A.C. Fevga will defend the doctoral thesis titled: ‘Navigating the Genetics of Movement Disorders from a Family-based Standpoint‘.
- Promotor
- Co-promotor
- Date
- Tuesday 19 Mar 2024, 10:30 - 12:00
- Type
- PhD defence
- Space
- Professor Andries Querido room
- Building
- Education Center
- Location
- Erasmus MC
Brief summary of the doctoral thesis:
Movement disorders constitute a heterogeneous group of neurological syndromes presenting with either a paucity or excess of movement. This heterogeneity is evident not only at the clinical level but also involves the epidemiology, pathology, genetics, and underlying pathophysiological mechanisms. Previous studies have revealed a highly heterogeneous genetic landscape for movement disorders. Nevertheless, the majority of patients with movement disorders remain etiologically unsolved, suggesting that additional disease-causing variants and genes will be identified. Moreover, solid phenotype-genotype correlations have not yet been established for many genes implicated in monogenic movement disorders.
Within this thesis, the genetic characterization of different movement disorders, including Parkinson’s disease (PD), atypical parkinsonism, isolated dystonia, complex dystonia, and paroxysmal dystonia is described.
- More information
The public defence will begin exactly at 10.30 hrs. The doors will be closed once the public defence starts, latecomers can access the hall via the fourth floor. Due to the solemn nature of the ceremony, we recommend that you do not take children under the age of 6 to the first part of the ceremony.
