PhD defence S. (Sander) Spiekhout

The Sound of a Singel Bubble

On Wednesday 16 October 2024, S. Spiekhout will defend the doctoral thesis titled: The Sound of a Singel Bubble

Promotor
Prof.dr.ir. N. de Jong
Co-promotor
Dr.ir. J.G. Bosch
Co-promotor
Dr.ir. J. Voorneveld
Date
Wednesday 16 Oct 2024, 15:30 - 17:00
Type
PhD defence
Space
Professor Andries Querido room
Building
Education Center
Location
Erasmus MC
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Below is a brief summary of the dissertation: 

Microbubbles have a greater potential than their current usage as blood pool imaging agents. Envisioned future microbubble use cases include therapy and minimally-invasive blood pressure sensing. To realize these new directions for microbubbles, it is crucial to control their vibrational response to ultrasound. This vibrational response largely depends on the size of microbubbles, which can be controlled by producing them via microfluidic flow-focusing, but the vibrational response also depends on their mechanical shell parameters. This thesis is focused on characterizing the shell properties of single microbubbles, with a particular focus on realizing their potential as minimally-invasive blood pressure sensor. Firstly we are interested in understanding the (variance in) acoustical response of monodisperse microbubbles. Secondly we are interested how microbubbles can be used to sense ambient pressure through subharmonics oscillations.

More information

The public defence will start exactly at 15.30pm. The doors will be closed once the public defence starts, latecomers can access the hall via the fourth floor. Given the solemn nature of the meeting, we advise not to bring children under the age of 6 to the first part of the ceremony. 
A livestream link has been provided to candidate. 

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