PhD defence N.J. (Nicolien) Schepers

Optimal Treatment of Acute Biliary Pancreatitis
Promotor
Prof.dr. M.J. Bruno
Promotor
Prof.dr. M.G.H. Besselink
Co-promotor
Dr. O.J. Bakker
Date
Tuesday 8 Oct 2024, 13:00 - 14:30
Type
PhD defence
Space
Professor Andries Querido room
Building
Education Center
Location
Erasmus MC
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On Tuesday 8 October 2024, N.J. Schepers will defend the doctoral thesis titled: ‘Optimal Treatment of Acute Biliary Pancreatitis'.

Brief summary: 

This thesis aims to optimize the management of acute pancreatitis with a focus on patients with a biliary etiology. First we study two severe complication in acute pancreatitis:

  1. Cholangitis: we study the definition of cholangitis in patients with acute biliary pancreatitis
  2. Organ failure: we describe the characteristics of organ failure en investigate and the effect on mortality 

We then discuss the role of early endoscopic intervention by means of endoscopic retrograde cholangiography in acute biliary pancreatitis. Based on the results of the multicenter, randomized APEC-trial, we conclude that there is no role for early ERCP in patients with acute biliary pancreatitis, without cholangitis. Finally, we focus on preventing recurrent biliary complications after an episode of acute biliary pancreatitis, in which early cholecystectomy plays a central role.

More information

The public defence will begin exactly at 13.00 hrs. The doors will be closed once the public defence starts, latecomers can access the hall via the fourth floor. Due to the solemn nature of the ceremony, children under the age of 6 are not allowed during the first part of the ceremony. 

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