PhD defence M.P. (Matthijs) Raadsen

Coronavirus-Associated Disease in Humans From critical illness to vaccines

On Tuesday 18 Februay 2025, M.P. Raadsen will defend the doctoral thesis titled:  Coronavirus-Associated Disease in Humans
From critical illness to vaccines

Promotor
Prof. Dr. E.C.M. van Gorp
Co-promotor
Dr. B.L. Haagmans
Co-promotor
Dr. M. Goeijenbier
Date
Tuesday 18 Feb 2025, 13:00 - 14:30
Type
PhD defence
Space
Professor Andries Querido room
Building
Education Center
Location
Erasmus MC
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Below is a brief summary of the dissertation: 

My dissertation is about coronaviruses and their impact on human health. It consists of 13 chapters, based on 9 scientific publications. In the introduction, I describe where coronaviruses come from and how they can adapt to humans. Then it goes on to talk about how COVID-19 could cause severe inflammation and blood clots in some people at the beginning of the pandemic. The last part is about how coronavirus infections in humans can be prevented by vaccination. 
The most important research in this dissertation is about the MERS coronavirus, which was discovered in 2012. This virus causes severe pneumonia, and is lethal for about 36% of patients who become infected. Erasmus MC, together with researchers in Germany, has developed a vaccine against this virus, and tested it on healthy volunteers between the ages of 18 and 55 in Hamburg and Rotterdam. These volunteers experienced only mild side effects from the vaccine, and developed antibodies against the MERS coronavirus. This research is important because it prepares us for possible future pandemics.

More information

The public defence will start exactly at 13.00 hrs. The doors will be closed once the public defence starts, latecomers can access the hall via the fourth floor. Given the solemn nature of the meeting, we advise not to bring children under the age of 6 to the first part of the ceremony. 
A livestream link has been provided to candidate. 

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