PhD defence J.R. (Jelle) Miedema

Adaptive Immune Responses and Treatment in Sarcoidosis and Pulmonary Fibrosis: The road towards personalized medicine

On Tuesday 5 November 2024, J.R. Miedema will defend the doctoral thesis titled: Adaptive Immune Responses and Treatment in Sarcoidosis and Pulmonary Fibrosis: The road towards personalized medicine

Promotor
Prof. dr. R.W. Hendriks
Professor
Prof. dr. M.S. Wijsenbeek-Lourens
Date
Tuesday 5 Nov 2024, 15:30 - 17:00
Type
PhD defence
Space
Professor Andries Querido room
Building
Education Center
Location
Erasmus MC
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Below is a brief summary of the dissertation:

In this thesis, we focused on the adaptive immune responses and new personalized treatment in sarcoidosis and pulmonary fibrosis. We aimed to (I) identify new T cell biomarkers in sarcoidosis that may correlate with long-term prognosis or favorable response to specific treatment and (II) unravel the role of aberrantly activated T cells in sarcoidosis pathogenesis using a novel mouse model. Furthermore, we aimed to (III) investigate the safety and efficacy of antifibrotic therapy in progressive pulmonary fibrosis due to asbestosis in a small sample size study, using daily home monitoring of forced vital capacity (FVC).

More information

The public defence will start exactly at 15.30hrs. The doors will be closed once the public defence starts, latecomers can access the hall via the fourth floor. Given the solemn nature of the meeting, we advise not to bring children under the age of 6 to the first part of the ceremony. 
A livestream link has been provided to candidate. 

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