PhD defence I. (Ibtissam) Acem

Towards Patient-tailored care for Soft Tissue Sarcoma
Promotor
Prof.dr. C. Verhoef
Promotor
Prof.dr. M.A.J. van de Sande
Co-promotor
Dr. D.J. Grünhagen
Co-promotor
Dr. W.J. van Houdt
Date
Wednesday 29 May 2024, 10:30 - 12:00
Type
PhD defence
Space
Professor Andries Querido room
Building
Education Center
Location
Erasmus MC
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On Wednesday 29 May 2024, I. Acem will defend the doctoral thesis titled: ‘Towards Patient-tailored care for Soft Tissue Sarcoma‘.

Brief summary of the doctoral thesis:

Over the past few decades, there has been a paradigm shift in cancer research from focusing on the homogeneity within a patient population to emphasizing the diversity or heterogeneity in presentation and clinical outcomes among patients. This concept has been commonly referred to as personalised medicine. The foundation of personalised medicine lies in delivering effective care tailored to each individual patient. In this thesis, we aimed to contribute to a more personalised and patient-tailored approach in the management of patients with soft tissue sarcoma (STS), a rare type of cancer. We achieved this goal by  developing and validating different prediction tools and assessing how prediction tools could play a role in the clinical decision making process for STS. The following three main questions were addressed in this thesis:

1. PART I: Given the current practice,
what is the variation in clinical presentation and oncological outcome of patients with STS? 
which factors influence this variation in oncological outcome?
2. PART II: How to better identify patients at risk and predict oncological outcome in patients with STS?
3. PART III: How could prognostic tools play a role in the clinical decision making and management of STS?

More information

The public defence will begin exactly at 10.30/13.00/15.30 hrs. The doors will be closed once the public defence starts, latecomers can access the hall via the fourth floor. Due to the solemn nature of the ceremony, children under the age of 6 are not allowed during the first part of the ceremony.

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