PhD defence T.V. (Theresa) Feddersen

MR Thermometry for Hyperthermia in the Head and Neck

On Tuesday 23 January 2024, T.V. Feddersen will defend the doctoral thesis titled: ‘MR Thermometry for Hyperthermia in the Head and Neck‘.

Promotor
Prof.dr. G.C. van Rhoon
Promotor
Prof.dr. J.A. Hernandez Tamames
Promotor
Prof.dr.ir. M.M. Paulides
Co-promotor
Dr.ir. D.H.J. Poot
Date
Tuesday 23 Jan 2024, 13:00 - 14:30
Type
PhD defence
Space
Professor Andries Querido room
Building
Education Center
Location
Erasmus MC
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Brief summary on the aim of the doctoral thesis:

Hyperthermia is a cancer treatment which consists of heating the tumour to 39-43°C. When clinically possible, the temperature during the treatment is measured by placing temperature probes intraluminal or invasively. The only possibility to measure the 3D temperature distribution non-invasively in and around deep-seated tumours is by magnetic resonance thermometry (MRT). 

Current applications of MRT in hyperthermia mainly include anatomical regions that are not influenced by motion, such as sarcomas in extremities, or as adjuvant to invasive probe-based approaches. Motion-rich anatomy is difficult to image with MRI and also non-local organ motion due to, e.g., respiration can lead to large artifacts. 

Recently, we have started the development of an MR-compatible hyperthermia applicator for the head and neck. Because it is the first device of its kind, there is very little experience on MRT in this anatomical region. In this project we investigated how we can improve and adapt MRT to the difficult anatomy in the head and neck.

More information

The public defence will begin exactly at 13.00 hrs. The doors will be closed once the public defence starts, latecomers can access the hall via the fourth floor. Due to the solemn nature of the ceremony, we recommend that you do not take children under the age of 6 to the first part of the ceremony.

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